Overview of Pemphigus
Pemphigus of the skin and mucous membranes is a chronic blistering disease most commonly found in middle-aged persons.
There are three major types of pemphigus:
- Vulgaris (literally meaning common)
- Foliaceus (featuring superficial blisters)
- Paraneoplastic (associated with some cancers)
Pemphigus is an autoimmune disorder in which the skin cells are attacked by the patient's own antibodies (immune proteins). This causes a separation between the layers of skin in which fluid subsequently accumulates, producing blisters. The introduction of corticosteroids in recent decades has turned what often had been a fatal disease into one that can be managed quite well.