Signs and Symptoms of Bone Cancer

The most common symptom of bone cancer is bone pain, which may worsen at night and with activity, and cause a limp, if the cancer occurs in the leg. In some cases, a lump develops on the bone. Bone cancer may weaken the affected bone, sometimes resulting in a fracture.

Other general symptoms include the following:

  • Anemia (reduced red blood cell count)
  • Fatigue
  • Fever
  • Swelling
  • Tenderness
  • Weight loss

Publication Review By: Stanley J. Swierzewski, III, M.D.

Published: 11 Sep 2006

Last Modified: 02 Sep 2015