Researchers assigned 641 patients with chronic fatigue syndrome to 52 weeks of one of four therapies:
- Standard medical care (written generic advice);
- adaptive pacing (strategies for adapting to the condition, such as prioritizing activities, limiting stress and conserving energy);
- cognitive behavioral therapy (learning how to change behaviors, such as avoiding physical activity); and
- graded exercise (incrementally increasing activity up to normal levels).
Only those who participated in cognitive behavioral therapy or graded exercise reported less fatigue and improved physical function.
Source: The Lancet, vol. 377, p. 823; Prepared by the Editors of The Johns Hopkins Medical Letter: Health After 50