| abduct | motion of a body part away from the midline of the body |
| abscess | localized pocket or collection of pus in a cavity |
| absorbent products | pads and garments, disposable or reusable, worn in cases of incontinence to absorb leaked urine |
| Achilles tendon | tendon formed by the union of two muscles,the gastrocnemius and the soleus, which join in the mid-calf area and are known as the gastroc-soleal complex; prominent at the back of the ankle |
| Achilles tendonitis | painful and often debilitating inflammation of the Achilles tendon |
| actinic keratosis | common precancerous skin growth |
| adduct | motion of a body part toward the midline of the body |
| adjuvant | assisting the primary means of therapy, e.g., coupling radiation treatment with surgical excision of tumors |
| AIDS | acquired immunodeficiency syndrome |
| allergen | substance inducing an allergic state or reaction |
| allergic contact dermatitis |
dermatitis caused by sensitivity to an allergen |
| allergy | inappropriate or exaggerated reaction of the immune system to substances that cause no symptoms in most people, e.g., reactions to chemical exposure, respiratory reactions to dust, pollen or other substances, reactions to food |
| alopecia | hair loss; disease in which the hair falls out |
| alternative therapy | therapy that is not standard, including herbal medicines, acupuncture, and acupressure, as well as medicinal therapies, such as shark cartilage, maitake mushroom, etc. |
| Alzheimer's disease | most common form of dementia in older persons that affects many areas of cognitive function, including memory |
| amyotrophic lateral sclerosis (ALS) |
degenerative disorder affecting the motor neuron cells and the motor tracts in the brain and spinal cord; Lou Gehrig's disease |
| anaphylaxis | severe, life-threatening allergic reaction, such as that caused by an insect sting or exposure to a drug, like penicillin or antitetanus (horse) serum, or that caused by certain foods, like peanuts or shellfish; anaphylactic shock |
| anemia | deficiency in red blood cell count, in hemoglobin, or in total blood volume |
| angina | discomfort and pain felt when a blockage in a coronary artery prevents oxygen-rich blood from reaching part of the heart |
| angiogram | invasive diagnostic test whereby a dye is injected into the arteries through a catheter in order to observe the blood vessels |
| angioplasty | procedure for treating blockages and blood clots in which a small balloon is inflated to open clogged arteries |
| ankle joint | joint made by the two leg bones (the tibia and the fibula) and the most superior bone in the foot (the talus) |
| annular | ringlike |
| antiarrhythmic agents |
drugs that slow or eliminate rapid contraction of the ventricle |
| antibody | protein produced in a controlled manner by certain white blood cells (lymphocytes) to neutralize an antigen or foreign protein and fight disease, but whose uncontrolled production can cause illness; immunoglobulin |
| anticholinergics | quick-relief asthma medications that work by inhibiting nerve receptors in the airways and by blocking reflex bronchoconstriction of the nervous system |
| antigen | substance that can trigger an immune response, resulting in production of an antibody as part of the body's defense against infection and disease; allergen |
| antihistamines | drugs that block the effects of histamine, a chemical released in body fluids during an allergic reaction, and which reduce itching, sneezing, and runny nose |
| anti-inflammatory agents |
drugs that reduce inflammation and its effects |
| anxiety | generalized feeling of apprehension, fear, or worry that interferes with normal life functions |
| aortic valve | one-way valve that allows blood to flow only out of the left ventricle and into the aorta |
| aphasia | acquired abnormality in the production or comprehension of language |
| apnea | condition in which the upper airway tends to collapse repeatedly while sleeping |
| appendicolith | small hard stone often seen in the appendix that is generally composed of enough calcium to be seen on x-rays and particularly on CT scans |
| applecore (lesion) | appearance of the typical annular-shaped cancer of the colon whose concentric growth around the tubular large bowel resembles an eaten apple |
| arrhythmia | irregular heartbeat that features either very rapid ventricular contractions (tachycardia), an excessively slow heartbeat (bradychardia) or, most commonly, extra or "premature" beats |
| arteries | blood vessels that carry oxygenated blood from the lungs to the organs |
| articulate | process by which two adjacent bones form a joint and slide upon each other |
| artifact | various types of image distortion and interference found in x-ray film |
| artificial urinary sphincter (AUS) |
surgically implanted device (consisting of three parts: pump, balloon reservoir, and cuff) that is used to control the involuntary release of urine associated with prostate and urinary tract surgery |
| assisted reproductive technologies (ART) |
fertility treatments that incorporate methods of sperm retrieval and preparation: artificial insemination (AI), in vitro fertilization (IVF), and sperm microinjection techniques |
| asthma | chronic, inflammatory lung disease triggered by allergens, infection, exercise, cold air, and other factors that cause narrowing of the airways, breathing difficulty, coughing, and wheezing |
| ataxia telangiectasia (AT) |
progressive, degenerative genetic disease, which causes degeneration of the nervous system, cancer, and immunodeficiency |
| atherosclerosis | condition in which lipids (fats) collect under the inner lining of damaged artery walls, eventually narrowing or blocking the artery and obstructing blood flow |
| athlete's foot | common, irritating, often persistent infection of the foot caused by a dermatophyte (microscopic moldlike fungus) that lives on dead tissues of hair, toenails, and outer skin layers |
| atony | lack of muscle tone, usually leading to temporary weakness |
| atopy | hereditary presence of antibodies associated with allergic reactions |
| atria (sing., atrium) | right and left upper chambers of the heart |
| atrial fibrillation | abnormal rhythm of the heart that can result in an increased risk of stroke due to the formation of emboli (blood clots) in the heart |
| atrophy | wasting of tissue, cell, or organ |
| aura | warning symptoms like disturbances in vision, strange smells, or hallucinations that occur prior to a particular neurological event, such as seizure or migraine |
| autism | lifelong developmental disability that occurs by itself or in association with other disorders that affect the function of the brain, such as viral infections, metabolic disturbances, mental retardation, epilepsy, and fragile X syndrome; characterized by severely impaired social interaction and communication skills and restrictive or repetitive movements, interests, and behaviors |
| autoimmune | abnormal response of the immune system that causes antibodies and immune-mediated cells to attack one's own tissues |
| autologous | derived from or originating in an individual |
| AV node (atrioventricular node) |
patch of electrical-wire-like specialized heart tissue located between the atria and the ventricles that conducts contractile impulses from the atria to the ventricles |
| axon | inner core of peripheral nerves |
| BAEP | see brainstem auditory evoked potential |
| basal cell carcinoma | most common skin cancer, derived from the basal cell |
| basal cells | cells that form the bottom layer of the epidermis |
| basal ganglia | series of structures located deep in the brain that are responsible for motor movements |
| behavioral modification techniques |
See biofeedback, bladder training, habit training, pelvic muscle exercises. |
| Bell's palsy | paralysis of the facial nerve producing distortion on one side of the face |
| benign prostatic hyperplasia |
enlargement of the prostate associated with aging |
| benign | not cancerous |
| beta2 agonists | quick-relief medications that cause muscle relaxation and bronchoexpansion to relieve acute asthma symptoms |
| beta-blockers | drugs that relieve stress on the heart by "blocking" the stimulating effect of adrenaline |
| bifurcation | division of a single structure (usually vascular) into two paired structures, e.g., carotid bifurcation in the neck, where the common carotid arteries divide into the internal and external carotid arteries |
| bilateral | affecting both sides of the body or two paired organs, e.g., the kidneys |
| biofeedback | therapeutic training in which participants learn to control their involuntary nervous system through response to electric stimuli |
| biologic therapy | systemic therapy utilizing interferon or interleukin |
| biopsy | (v.) to remove a sample of tissue for diagnostic evaluation; (n.) tissue specimen |
| bladder training | behavioral modification technique used to resist or inhibit the urge to urinate unpredictably |
| bladder | hollow, muscular, balloon-shaped organ that stores urine until it is excreted |
| blanch | to make white or pale; to take color out |
| blepharospasm | involuntary closure of the eyes and lids |
| blood clot | insoluble mass of blood |
| blood culture | laboratory examination of a blood sample to detect the presence of disease-causing microorganisms |
| blood pressure measurement |
measure of the force of blood flow against artery walls taken with an inflatable cuff, inflating bulb, and a pressure gauge |
| blood thinners | drugs that inhibit blood clotting |
| bone | hard type of connective tissue, primarily made up of osteoblasts, osteocytes, and collagen, that supports and protects the body |
| bone scan | nuclear medicine study used for detecting the presence of boney metastasis |
| bone survey | radiologic study used to detect fractures and/or areas of boney destruction |
| brachymetatarsia | condition in which one of the metatarsals (the five long bones of the foot) is abnormally short, making the toe short as well |
| brachytherapy | radioactive pellets applied to the body area being treated; used to treat some cancers |
| bradykinesia | slowing of motor movements due to dysfunction of the basal ganglia and related structures |
| brain attack | see stroke |
| brain injury | (1) closed head injury (CHI), which is caused by rapid acceleration and deceleration of the head during which the brain bounces off the inside of the skull; (2) open head injury (OHI), caused by car accident, gunshot wound, or other external factor |
| brainstem auditory evoked potential |
test that measures how much auditory stimulus is required to cause a response from the brainstem |
| breast | modified sweat gland that produces milk during pregnancy |
| bronchial provocation | test used to diagnose asthma; also bronchoprovocation, bronchial challenge |
| bronchitis | inflammation of the bronchi (lung airways) that causes a persistent cough and sputum (phlegm) production; especially common in smokers and in areas with atmospheric pollution |
| bronchoconstriction | constriction of the bronchial airways in the lungs, causing shortness of breath, tightness in the chest, coughing, and wheezing |
| bronchodilator drugs | group of drugs that widen the airways in the lungs |
| bronchus (pl., bronchi) |
any of the larger air passages connecting the trachea (windpipe) to the lungs |
| bulla (pl., bullae) | sharply circumscribed, elevated, fluid-filled lesions in the skin that are over 0.5 centimeters in diameter; blister |
| bunion | bulge or bump that develops on the inner side of the foot, near the base of the first toe, caused by poor alignment of the metatarsal-phalangeal joint of the big toe, or hallux |
| bursa | sac of fluid typically found in areas where muscles or tendons tend to rub against bone, such as the hip, knee, and ankle |
| bursitis | condition in which a bursal sac becomes inflamed due to irritation |
| calcaneus | heel bone, the largest bone in the foot |
| calcifications | hard, dense, stonelike material that forms in numerous areas throughout the body, including arteries (plaque), veins (phleboliths), kidneys (stones), and gallbladder (gallstones) |
| calcium-channel blockers |
drugs that limit calcium entry into the cells and stimulate contraction |
| callus | area of skin that grows thick in response to repeated pressure and friction |
| candidiasis | infection of the skin, mucous membranes, and sometimes internal organs with the yeast Candida |
| carbuncle | deep-seated infection involving a cluster of hair follicles, often accompanied by a large area of redness and swelling |
| carcinoma | type of cancer that has the ability to spread, or metastatsize, to other areas of the body |
| cardiac catheterization | diagnostic procedure using a flexible tube, or catheter, that is passed into the heart through a vein or an artery in order to withdraw samples of blood, measure pressures within the heart chambers or vessels, and inject x-ray contrast materials to view the heart |
| cardiac transplantation | replacement of a damaged or diseased heart with a healthy heart from a donor who has died of other causes |
| carotid arteries | paired (right and left) arteries that arise from the aorta or branch of the thoracic aorta; external carotid arteries in the neck supply blood to structures in the face, internal carotid arteries supply blood to much of the front of the brain |
| cartilage | type of connective tissue found on the ends of bones, which protects and cushions them, and absorbs the forces transmitted throughout the body; living tissue without a direct blood supply |
| CAT scan (computerized axial tomography) |
specialized x-ray examination that is often used to visualize the brain and spinal structures, chest, abdomen, and pelvis |
| cataplexy | sudden loss of postural tone, often resulting in complete collapse; common in narcolepsy or intense emotional response |
| catheter | tube passed through the body for draining fluids, injecting fluids into body cavities, and performing certain tests |
| catheterization | insertion of a catheter |
| cecum | beginning of the large bowel where the end of the small bowel (ileum) empties into the cecum at the ileocecal valve |
| central nervous system |
the brain and the spinal cord |
| cerebral aneurysm | weakness in the wall of a blood vessel in the brain |
| cerebrospinal fluid | fluid that surrounds the brain and the spinal cord |
| cerebrovascular disease |
disorders of the blood vessels that supply the brain |
| chancre | hard, syphilitic, primary ulcer, usually occurring singularly; first sign of syphilis |
| charcot foot | severe collapse and fracturing of the foot, seen most often in diabetic patients with neurological problems |
| Charcot-Marie- Tooth disease |
progressive debilitating neuromuscular disorder; also hereditary motor sensory neuropathy and peroneal muscular atrophy |
| chemolysis | destruction through the use of chemicals; chemical injection treatment to dissolve kidney stones |
| chest pain | see angina |
| cholesterol | soft, waxy type of fatty particle (lipid) that circulates in the blood; building block for all cell membranes and many sex hormones |
| circle of Willis | circle of arteries at the base of the brain that is fed by the two paired internal carotid arteries and the two paired vertebral arteries |
| clonus | increase in involuntary muscle tone and subsequent movement that results in spasm |
| cluster headache | one-sided severe pain around the eye that usually occurs at night; associated with nasal stuffiness and tearing of the eye |
| cm | centimeter |
| colon | tubular structure from the stomach to the anus that consists of the small intestine and the large intestine |
| colonoscopy | test in which a length of fiberoptic tubing is inserted into the rectum and passed into the beginning of the large bowel (cecum), allowing the physician to directly visualize the bowel walls |
| coma | state of unconsciousness, with the eyes closed |
| comedo (pl., comedones) |
thickened secretion of dead skin cells and oily material plugging a follicle or pore; closed (whiteheads), open (blackheads) |
| computerized axial tomography |
see CAT scan |
| congestive heart failure (CHF) |
potentially lethal condition in which congestion develops in the lungs that is produced by a heart attack, poorly controlled or uncontrolled hypertension, or disease processes that weaken the heart |
| conscious sedation | medication that allows a patient to sustain what could be an unpleasant experience by producing "grogginess" and often complete amnesia of the event |
| contact dermatitis | reaction that occurs when the skin comes into contact with a substance to which the body is allergic |
| cor pulmonale | enlargement and eventual failure of the right ventricle of the heart, caused by lung disease |
| core needle biopsy | used by a pathologist to detect abnormality in tissue |
| corns | thickened areas of skin that form in response to excessive pressure and friction, usually hard and round, with a polished or translucent center, like a kernel of corn |
| coronary angiography | x-ray imaging of the coronary arteries through a catheter |
| corpora cavernosa | two spongy tissue chambers of the penis that run the length of the organ; tissue that fills with blood during an erection |
| corticospinal tract | nervous system structures that begin in the brain and travel to the motor neuron cell to innervate the motor nerves |
| corticosteroids | group of anti-inflammatory drugs similar to natural hormones produced by the cortex of the adrenal glands |
| creatinine | waste product filtered from the blood by the kidneys and expelled in urine |
| Crohn's disease | inflammatory disease most prominent in the small bowel, which may involve any part of the gastrointestinal tract and other organs, and which is associated clinically with diarrhea and irritable bowel; regional ileitis |
| crust | scablike coating of dried blood, pus, or drainage that covers wounds or damaged skin |
| cryosurgery | destruction of a skin lesion by applying liquid nitrogen |
| cryotherapy | therapeutic use of cold |
| CT KUB | computerized tomography of the abdomen and pelvis in which no oral or intravenous dyes are used, which is often used to detect conditions such as acute appendicitis, renal or ureteral stones, and diverticulitis |
| CT scan | see CAT scan |
| curettage and desiccation |
surgical technique in which a curette is used to scrape tissue, followed by drying and burning of that tissue with electrocautery |
| curette | surgical instrument with a round, hollow, sharp tip that is used to scrape tissues |
| cutaneous T-cell lymphoma (CTCL) |
cancer of the T cells, often confined to the skin but has the ability to spread |
| cutaneous | related to the skin |
| cyst | sac that contains semisolid or liquid contents |
| cystectomy | surgical removal of the bladder |
| cystocele | herniation of the bladder into the vagina |
| cystoscopy | procedure using a flexible scope inserted into the urethra and then into the bladder to determine abnormalities in the bladder and lower urinary tract |
| dander | minute scales from hair, feathers, or skin that may be allergenic |
| de novo | in a new manner or form |
| deep tendon reflexes | deep muscle stretch reflexes that are triggered by tapping on the tendons; the "knee jerk" |
| deltoid ligament | complex of four ligaments (anterior tibiotalar, tibionavicular, tibiocalcalcaneal, and posterior tibiotalar) that helps support the medial side of the ankle joint |
| dementia | acquired loss of cognitive function that may affect language, attention, memory, personality, and abstract reasoning |
| demyelination | destruction of myelin sheath that envelopes nervous system structures |
| density | densities on plain x-rays vary from black to white, depending on the composition of the material the x-rays pass through; black indicates the lowest x-ray density (air) and white, the highest (bone) |
| depigmentation | loss of pigment, especially melanin |
| dermatitis | inflammation and irritation of the skin |
| dermis | second layer of skin made up of a network of collagen and elastic fibers, blood vessels, and nerves |
| DESD | see detrusor-external sphincter dyssynergia |
| desiccate | to dry up |
| detrusor-external sphincter dyssynergia (DESD) |
lack of coordination between the bladder and the external sphincter muscle, resulting in the inability to empty the bladder completely, which may cause severe urinary tract damage and life-threatening consequences |
| diabetes mellitus | common form of diabetes in which the body cannot properly store or use glucose (sugar), the body's main source of energy |
| diastolic pressure | arterial pressure measured while the heart rests between beats |
| digoxin or digitalis | drug used to treat congestive heart failure by increasing the force of contraction; used to treat atrial fibrillation by slowing transmission of atrial electrical impulses (i.e., slowing the heart rate) and restoring normal heart rate |
| disease-free survival | percentage of disease survivors still alive after a specified period of time |
| diuretic | drug used to treat high blood pressure and fluid retention by increasing the elimination of salt and water by the kidneys |
| diverticulum | small outpouching of the lining of various tubular structures in the body |
| DNA | deoxyribonucleic acid, the genetic blueprint in all of our cells |
| dorsiflex | upward motion of a body part |
| duodenum | first segment of the small bowel |
| dust mites | microscopic organisms that feed on dead skin, whose feces are a common environmental allergen that can trigger asthma |
| echocardiogram | record produced by echocardiography |
| echocardiography | noninvasive cardiac imaging procedure used to diagnose heart disease, valve disorders (valvular heart disease), weakened heart muscle, fluid around the heart (pericarditis), and other abnormalities or defects by reflecting sound waves off the heart |
| eczema | disorder of the skin characterized by inflammation, itching, blisters, and scales |
| edema | swelling as a result of fluid retention |
| EEG (electroencephalogram) |
test used to study brain wave activity, often used to evaluate seizure disorders |
| ejaculation | ejection of semen during male orgasm |
| ejection fraction | percentage of blood that is ejected out of the left ventricle into the aorta with each heart beat |
| electrocardiography/ electrocardiogram (ECG, EKG) |
graphical recording of the electrical currents that pass through the heart muscle during each heartbeat; commonly called an EKG because the procedure was developed in the Netherlands, where it was spelled "electrokardiogram" |
| electrohydraulic lithotripsy (EHL) |
technique that uses small shock waves to break up small kidney stones |
| electron-beam radiation | radiation therapy in which the beams penetrate the skin only, thus limiting internal side effects |
| EMG/NCV (electromyography/ nerve conduction study) |
test to study the nerves and muscles for diagnosis of disorder, with electrical conduction studied in the NCV |
| encephalitis | inflammation or infection of the brain |
| endocarditis | inflammation and infection of a heart valve or the lining of the heart's chambers |
| endothelium | layer of epithelial cells that lines the cavities of the heart, blood vessels, and the serous cavities of the body |
| enterocele | herniation of the small bowel into the vagina |
| epidermis | top layer of skin, composed mainly of squamous cells, as well as basal cells, melanocytes, and other types of cells |
| epididymis (pl., epididymes) |
coiled tube that extends the length of each testis and connects with the vas deferens |
| epilepsy | episodic disorder resulting from temporary brain dysfunction which produces convulsive or nonconvulsive seizures |
| erosion | moist, slightly depressed area of skin where the top layer (epidermis) has been removed |
| erythema | redness and warming of the skin, typically due to inflammation caused by trauma or infection |
| erythroderma | diffuse reddening of the skin, caused by one of many disorders including psoriasis, eczema, drug sensitivities, and lymphoma |
| esophagus | muscular tube that begins at the back of the throat, passes through the neck and chest, and enters the stomach at the gastroesophageal junction just below the diaphragm |
| esphagogastric- duodenoscopy (EGD) |
test to observe the esophagus, stomach, and portion of the small intestine |
| estrogen | hormone produced by the ovaries that is responsible for the development of female sex characteristics |
| eversion | motion of a body part as it tilts away from the midline |
| evoked potentials | series of electrophysiological tests to evaluate the function of specific nervous system elements associated with multiple sclerosis |
| exacerbation | worsening of symptoms |
| excise | to cut out |
| excisional biopsy | surgical removal of tissue for pathological analysis |
| exfoliation | shedding of the top layers of the epidermis |
| external-beam radiation therapy |
treatment that utilizes external-beam radiation |
| extracorporeal shock wave lithotripsy (ESWL) |
highly focused electrical impulses that are projected from outside the body to pulverize kidney stones |
| extrinsic asthma | asthma triggered by an allergic reaction, usually something that is inhaled |
| fasciculation | twitching of the muscles that is seen in diseases of the peripheral nervous system |
| fibrillation | uncontrolled rapid contraction of the fibers in the heart that occurs in the atrial, or upper, chambers (atrial fibrillation) and in the ventricular, or lower, chambers (ventricular fibrillation) |
| fibrosis | formation of fibrous (scar) tissue after an injury |
| fine needle aspirate (FNA) |
insertion of small gauge needle into an area of abnormality with an attempt to suck out small amounts of tumor for review by a pathologist |
| first metatarsal phalangeal joint (1st MTJ) |
where the big toe connects to the foot; common site for the development of osteoarthritis |
| fissure | linear split or crack, usually in areas of chronic inflammation and skin thickening such as calluses on hands and feet |
| flexible sigmoidoscopy | insertion of a small-sized tube into the rectum to visualize the rectum and a portion of the colon |
| follicle (hair follicle) | tiny tubular structure in the skin, contiguous with the top skin layer, or epidermis, that includes the canal, the hair shaft, the sebaceous (oil) gland, and the muscle anchored to the follicle's side wall |
| folliculitis | inflammation with or without infection of the hair follicle |
| fungus (p., fungi) | member of a group of simple plantlike organisms that do not have leaves or flowers and that live off organic matter such as hair, skin, and nail cells of humans, animals, and plants |
| furuncle | deep inflammation and infection of the hair follicle |
| gadolinium | contrast agent that is given intravenously during MRI (magnetic resonance imaging) to increase visualization of specific abnormalities |
| gait | manner of walking |
| gallium scan | nuclear medicine study used to monitor gallium-avid lymphomas |
| gamma-knife radiation |
radiosurgery used most often to treat brain tumors and vascular lesions |
| gantry | the doughnut- or bagel-shaped device used for CT or MRI |
| gastroesophageal (GE) junction |
important junction between the esophagus and the stomach that normally permits one-way ingestion to the stomach |
| GI | gastrointestinal |
| gout | systemic disease caused by the buildup of uric acid crystals in the joints of the body, causing inflammation, swelling, and pain |
| grade | system used to classify the aggressiveness of a tumor |
| granulocytes | infection-fighting white blood cells (also called polymorphonuclear cells, PMNs, or polys) |
| Guillain-Barr� syndrome |
inflammatory disorder of the peripheral nerves characterized by rapid onset of weakness and often paralysis of the legs, arms, breathing muscles, and face.; acute idiopathic polyneuritis |
| habit training | behavioral modification technique that establishes scheduled toileting at regular intervals |
| hallux | proximal phalanx (end bone) of the first, big toe; site of many muscle attachments that, when imbalanced, contribute to the formation of a bunion |
| hammertoes | common deformity caused by a muscle imbalance in the foot |
| hay fever | See rhinitis. |
| heart attack | See myocardial infarction. |
| heart failure | See congestive heart failure. |
| heart murmur | whooshing sound caused by the turbulent flow of blood from the left ventricle across the mitral valve and back into the left atrium |
| heart transplant | See cardiac transplantation. |
| heel spur | condition in which a small piece of bone is pulled away from the calcaneus |
| hematemesis | act of vomiting blood |
| hematuria | blood in the urine, visible or microscopic |
| hemiparesis | weakness that affects one side of the body |
| hemoptysis | act of coughing up blood |
| hemorrhage | bleeding |
| heparin | drug that inhibits blood clotting |
| her2-neu | protein that indicates aggressive cancer, which is found in 30% of breast cancer patients |
| histamine | chemical present in cells throughout the body, which is released during an allergic reaction |
| HIV (human immunodeficiency virus) |
virus that affects the immune system and causes the disease known as AIDS (acquired immunodeficiency disorder) |
| homograft valve | aortic valve that has been taken from a human organ donor and used to replace a diseased heart valve |
| hormonal therapy | systemic therapy to block the action of specific hormones; use of antiandrogens to deprive cancer cells of the testosterone they need for growth |
| hospice | home-based health care and support for terminally ill patients and their families |
| hydrocele | painless swelling of the scrotum caused by a collection of fluid around the testicle; common in middle-aged men |
| hypercholesterolemia, or high cholesterol |
excessive or disproportionate amounts of lipids (fats) in the circulating blood, including low-density lipoproteins (LDL), high-density lipoproteins (HDL), and tryglicerides |
| hypermobility | inability of the pelvic floor muscles to provide the necessary support for the urethra and bladder neck, causing the bladder neck to drop when any downward pressure is applied, and leading to involuntary leakage |
| hyperpigmented | accentuation or increase of pigment |
| hyperplasia | excessive growth of normal cells of an organ |
| hypertension, or high blood pressure | increased resistance to blood flow through small blood vessels (arterioles), which forces the heart to work harder |
| hypopigmented | lessening or lightening of pigment |
| idiopathic | without a known cause |
| idiopathic pericarditis | inflammation of the tissues of the pericardium, with no known or detectable cause |
| immune cells | cells produced in our bodies that protect us from disease-causing agents by producing antibodies |
| immune system | collection of cells, proteins, and lymphatic tissues that help protect the body from potentially harmful, infectious microorganisms |
| immunity | insusceptibility that usually results from previous exposure to an infectious agent, either naturally or by vaccination |
| immunoglobulins | proteins found in blood and in tissue fluids that are produced by B-lymphocyte cells in the immune system and which bind to foreign substances in the body in order to destroy them; antibodies |
| immunotherapy | preventive, incrementally progressive, anti-inflammatory treatment for allergies to substances such as pollens, dust mites, fungi, and insect venom; allergy shots |
| incisional biopsy | surgical removal of tumor tissue through a small incision |
| inflammation | redness, swelling, heat, and pain in a tissue caused by injury, infection, or hypersensitivity to an allergen |
| insemination | deposition of semen into the uterus, cervix, or vagina |
| in-situ | confined to the top layer or epidermis; cancer that has not spread to deeper tissues and has minimal propensity to metastasize |
| interstim continence control therapy | therapy used to treat urge incontinence |
| interstitial laser | laser probe used to destroy prostatic tissue and to allow easier urination |
| intrinsic asthma | asthma that has no apparent external cause |
| intrinsic sphincter deficiency (ISD) | weakening of the urethra sphincter muscles |
| intussusception | when one section of intestine slips over the next, like a sheath |
| invasive procedure | medical examination that invades the body either by incision or by insertion of an instrument through the skin |
| inversion | motion of a body part as it tilts toward the midline |
| irritable bladder | involuntary contractions of muscles in the bladder that cause uncontrolled urination |
| irritant contact dermatitis | dermatitis caused by irritating chemicals that come into contact with the skin |
| ischemia | lack of blood flow to a part, often caused by constriction or obstruction of a blood vessel |
| isolated systolic hypertension | condition usually found in the elderly in which only the systolic blood pressure is elevated |
| Kegel exercises | exercises to strengthen the muscles of the pelvic floor in order to control urination and prevent leakage |
| keratoacanthoma | mostly benign, rapidly growing skin tumor that regresses spontaneously |
| kidney | one of a pair of organs located at the back of the abdominal cavity that makes urine through blood filtration |
| kidney stone | hard mass composed of urine elements that form in the kidneys |
| KOH | potassium hydroxide |
| KUB | kidney, ureter, bladder |
| lacunar | subtype of stroke that affects the deeper parts of the brain and involves the tiny perforating arteries |
| laparoscopic lymph node dissection (LLND) | procedure using a laparoscope to obtain a tissue sample of a lymph node(s) |
| laparoscopy | generally less invasive surgery that uses a laparoscope to visualize internal organs through a small incision |
| large bowel | three-foot section of the gastrointestinal tract beginning in the lower right side of the abdomen; the colon |
| laser | light amplification by stimulated emission of radiation; device that produces light in a coherent, intense beam |
| lateral | describes the plane or movement that inclines away from the center or midline; opposite of medial |
| lateral collateral ligaments | complex of three ligaments that helps support the lateral side of the ankle joint; consisting of the anterior talofibular, calcaneofibular, and the posterior talofibular ligaments |
| left ventricular assist device (LVAD) | complex pump that is implanted in the body to assist the left ventricle in pumping blood |
| ligament | substance made of fibrous tissue that helps connect and stabilize joints, strengthening the gap between two or more bones, cartilage, and/or muscles |
| liquid nitrogen | liquid form of nitrogen gas (-195 degrees Celsius) that is used to treat various skin lesions in cryosurgery |
| lithotripsy | procedure that uses ultrasonic shock waves to break up stones in the urinary tract so their fragments can be passed |
| lumbar puncture (spinal tap) | removal and analysis of some of the cerebrospinal fluid from the base of the spine, used to diagnose meningitis or nervous system syphilis |
| lung | organ (pair) of the thorax whose contractions and expansions during respiration deliver oxygen to the blood |
| Lyme disease | disease that affects the joints, nervous system, and heart that is transmitted by the deer tick and is caused by the bacteria Borrelia burgdorferi |
| macule | small area of skin different in color to the majority of the body, but flush with the surrounding skin |
| magnetic resonance imaging (MRI) | |
| malignant | cancerous tumor or other disease state that has a debilitating, unremitting course |
| medial | inclining toward the center or midline of the body; opposite of lateral |
| melanocytes | cells intermingled with the basal cells in the bottom layer of the epidermis that produce pigment globules known as melanin |
| melanoma | skin cancer that originates in a melanocyte |
| melena | blood in the stool, typically loosely formed or liquid |
| meningitis | inflammation or infection of the meninges, the three laminated ultrathin membranes surrounding the brain |
| menopause | period that marks the permanent cessation of menstrual activity, usually occurring between the ages of 40 and 58 |
| metastasis | spread of disease from one organ or part to another |
| metastasize | to spread from one part of the body to another, as in cancer |
| metastatic | pertaining to metastasis; cancer that has spread to either the lymph nodes (regionally metastatic) or organs, e.g., lung, liver, adrenal glands, bone, or brain (distant metastasis) |
| metatarsals | five bones that run from the center of the foot to the beginning of the toes |
| metered-dose inhaler (MDI) | most common device for administering quick-relief asthma medications, consisting of a tube-shaped mouthpiece connected to a canister that projects a measured amount of medication when actuated by the user |
| mg | milligram |
| midline | invisible reference line that runs longitudinally and divides any body or object in half |
| migraine | headache characterized by throbbing, one-sided pain, that may be associated with nausea, vomiting, and aura (sensory disturbances) |
| mitral valve | one-way valve that allows blood to pass from the left atrium into the left ventricle and normally prohibits its reentry |
| mixed incontinence | stress and urge incontinence occurring simultaneously |
| mL | milliliter |
| motor neuron cells | cells located in the spinal cord that give rise to nerves that supply the muscles |
| MRA (magnetic resonance angiography) | test in which an MRI scanner is used to focus on structures within which blood flows, such as the arteries in the neck, brain, and lungs |
| multi-infarct dementia | dementia that is caused by the cumulative affect of multiple strokes |
| multiple sclerosis (MS) | chronic neurological disorder that affects the central nervous system, i.e., the brain and spinal cord |
| muscular dystrophy | congenital (hereditary) disorder resulting in muscular weakness and dysfunction |
| myasthenia gravis | disorder affecting the space between the nerve and the muscle (neuromuscular junction) that results in transient motor weakness of the face and limbs |
| myelin | outer lipid (fatty) layer that covers nerves and nervous system pathways in the brain and spinal cord |
| myelosuppressive | therapy that diminishes white blood cell count |
| myocardial infarction | medical emergency that occurs when a blood clot forms suddenly in a coronary artery and blocks blood flow to an area of the heart; heart attack |
| myopathy | disease of muscular dysfunction, usually causing weakness and atrophy |
| nadir | lowest white blood cell count measured between chemotherapy treatments |
| narcolepsy | sleep disorder characterized by sudden and repeated attacks of sleep, usually accompanied by cataplexy, hypnogogic hallucination, and sleep paralysis |
| nebulizer | device used to deliver inhaled medications, in which an air compressor is used to blow an atomized medication through a mouthpiece or face mask |
| needle localization biopsy | needle marker is inserted to define abnormal area prior to biopsy |
| nephrectomy | removal of the kidney |
| nephrotomography | conventional tomograms of the kidneys, especially in small sections of the kidneys |
| neurofibromatosis | genetic disorder which causes skin lesions, cutaneous and subcutaneous tumors, and tumors on internal organs |
| neurons | nerve cells of the brain responsible for neurological function |
| neuropathy | condition resulting from damage to the peripheral nerves that results in weakness or sensory loss and pain in the arms, hand, legs, and feet |
| neutropenia | low level of neutrophils in the blood |
| neutropenic fevers | fever associated with low white blood cell count and low granulocyte count |
| neutrophil | most abundant type of white blood cell, or leukocyte, that is active in immune responses and inflammatory reactions |
| nevus (pl., nevi) | congenital skin lesion, e.g., mole, birthmark, etc. |
| nodule | elevated, solid mass or lump (up to 2 cm in diameter) that can be located in the epidermis, dermis, or the subcutaneous fat |
| noninvasive procedure | medical examination that does not penetrate the skin or invade the body, except for minor needle sticks |
| nonsteroidal anti-inflammatory drugs (NSAIDs) | drugs that act against inflammation, reduce fever, relieve muscle pain, and prevent blood clots |
| normal pressure hydrocephalus (NPH) | increase in pressure within the ventricles of the brain, causing dementia, gait difficulties, and urinary incontinence |
| nystagmus | jerking movement of the eyes associated with neurological disorder |
| occlusion | closure; in sleep apnea, closing of the airway at the back of the mouth or top of the throat |
| oncologist | physician specializing in cancer treatment |
| onychomycosis | fungal infection of the fingernails or toenails that causes thickened, discolored, and often brittle nails |
| open nephrolithotomy | surgical excision of kidney stones via the back or abdomen in which the kidney may be opened |
| orchiectomy | surgical removal of one or both of the testicles |
| orchitis | inflammation of the testicle |
| osteoarthritis | deterioration of cartilage in the joints |