Information about Carbonic Anhydrase Inhibitors Dosages, Precautions & Side Effects
Carbonic anhydrase inhibitors that are used in glaucoma treatment include:
- Azopt (brinzolamide); 1 eyedrop 2-3x/day
- Diamox (acetazolamide); Oral: 1 capsule 2x/day
- methazolamide; Oral: 50-100 mg 2-3x/day
- Trusopt (dorzolamide); 1 eyedrop 3x/day
When using carbonic anhydrase inhibitor eye drops, patients should wait 2 minutes before using any other eyedrops. When using oral medications, take with meals, and increase consumption of potassium-containing foods. These medications lower IOP (intraocular pressure) by decreasing the production of aqueous humor.
Tell your doctor about any medical conditions you may have, particularly kidney or liver disease. Tell your doctor if you are taking acetazolamide (Diamox), dichlorphenamide (Daranide), eye medications, methazolamide (Neptazane) or products that contain aspirin. Call your doctor if you develop:
- redness or swelling of eyes, lips, or tongue
- skin rash
- difficulty breathing or swallowing
- sore throat
- chest pain
Common side effects associated with carbonic anhydrase inhibitor eyedrops include cloudy vision, headache, tearing, burning, stinging, and red eyes. Systemic side effects, such as numbness and tingling of hands or feet, are more likely with the oral formulation.