Information about Topical Prostaglandins Dosages, Precautions & Side Effects

Topical prostaglandins that are used in glaucoma treatment include:

  • Lumigan (bimatoprost); 1 eyedrop/1x day
  • Travatan, Travatan Z (travoprost); 1 eyedrop/1x day
  • Xalatan (latanoprost); 1 eyedrop/1x day

Topical prostaglandins should be used in the evening. Patients should wait 2 minutes before using any other eyedrops. These glaucoma medications lower IOP by increasing the flow of aqueous humor out of the eye.

Tell your doctor about any medical conditions you may have, particularly liver or kidney disease. Use with caution if active eye inflammation is present. Some people experience a gradual change in the color of their treated eye to brown or darkening of the skin. Darkening or thickening of your eyelashes may also occur. These changes may be permanent. If only one eye is treated, the eyes may look different.

Call your doctor if your eye becomes inflamed or you develop:

  • pinkeye or redness or swelling of the eyelid
  • sensitivity to light
  • notice changes to the color of your iris, the skin around your eyes, or your eyelashes

Common side effects of topical prostaglandins include itching, dryness or burning eyes, eye pain or irritation, tearing, headaches.

Publication Review By: Susan B. Bressler, M.D., Harry A. Quigley, M.D., Oliver D. Schein, M.D., M.P.H.

Published: 04 Mar 2011

Last Modified: 07 Jan 2015