Lip Cancer Treatment

For early disease, surgery or radiation are the mainstays. The choice of one over the other depends on the size and location of the disease. Given the infrequency of spread to the lymph nodes, elective treatment of the neck is not necessarily required. In advanced disease (Stages 3 and 4), a combination of surgery and postoperative radiation is often required.

Alveolar Ridge and Retromolar Trigone Cancer Treatment

In early disease (Stages 1 and 2) surgery or radiation alone with elective neck treatment (secondary to the tendency for regional nodal spread) is most often utilized. For advanced stages, multimodality therapy with surgery and postoperative radiation is often used.

Floor of Mouth Cancer Treatment

Treatment of early disease (Stage 1 and 2) involves surgical resection. However, either surgery or radiation as single modalities of therapy may be utilized. In early disease, the treatment of the neck is controversial; some opt for elective neck treatment in clinically negative necks, while others take a wait-and-see approach, with treatment reserved for those who show development of disease. For advanced disease (Stages 3 and 4), combined modality treatment with surgery and radiation is recommended. Elective treatment of the neck is required in all cases of advanced disease.

Tongue Cancer Treatment

Use of either surgery or radiation in early stage disease yields comparable outcomes. In advanced disease, as in other oral cavity cancers, combined modality therapy with surgery and radiation is utilized.

Hard Palate Cancer Treatment

For both early and advanced disease, surgery is used for primary therapy. Radiation has a role in advanced disease, depending upon the closeness or involvement of surgical margins by tumor, evidence of nerve involvement or the presence of lymph node metastases.

Buccal Mucosa Cancer Treatment

Small lesions (T1 or T2) can be handled equally well by either surgery or radiation. For patients with small lesions and clinically negative necks, observation can be performed rather than treatment of the neck. For more advanced lesions, treatment of the neck is advisable. In advanced cancers, treatment most often consists of surgery followed by postoperative radiation.

See oral cancer for more information.

Publication Review By: Stanley J. Swierzewski, III, M.D.

Published: 14 Aug 1999

Last Modified: 18 Sep 2015