Cluster Headache Prevention

Prednisilone (Prednisone)

This is a steroid medication that is taken initially in high doses, then tapered over days to weeks, depending on the response. This medication is best if used for short periods of time, as long term steroid use is associated with many complications.

Lithium carbonate

This medication is taken orally, usually twice a day in order to interrupt the cluster. Laboratory testing including lithium levels should be followed closely. Side effects include tremor, increased thirst and gastrointestinal symptoms.

Verapamil

This is a medication that can also be effective in migraine. It can be taken twice daily in a sustained oral preparation. Side effects include dizziness and constipation.

Publication Review By: Stanley J. Swierzewski, III, M.D.

Published: 02 Jan 2002

Last Modified: 08 Jun 2010