Overview of Peyronie's Disease

Peyronie's disease is characterized by the formation of hardened tissue (fibrosis) in the penis that causes pain, curvature, and distortion, usually during erection. The penis is the male organ for reproduction and urination. It is composed of two columns of erectile tissue (the corpora cavernosa); the corpus spongiosum, which contains the tube that carries urine and semen from the body (urethra); and the sheath that surrounds the erectile tissue (tunica albuginea). In Peyronie's disease, dense, fibrous scar tissue (plaque) forms in the tunica albuginea.

Incidence and Prevalence of Peyronie's Disease

According to the National Institutes of Health (NIH), Peyronie's disease occurs in about 1 to 23 percent of men between the ages of 40 and 70. However, the actual occurrence of the condition may be higher due to a reluctance to seek medical attention for the condition and failure to report minor cases.

The chance of developing Peyronie’s disease increases with age. It is most common between the ages of 45 and 60, but it also occurs in younger and older men.

Publication Review By: Barton H. Wachs, M.D., F.A.C.S., Stanley J. Swierzewski, III, M.D.

Published: 14 Jun 1998

Last Modified: 29 Sep 2015