Causes and Risk Factors for Pyloric Stenosis

The exact cause for pyloric stenosis is unknown. Researchers believe that genetics are involved, as the condition often runs in families. Possible causes that are under investigation include the following:

  • Allergic reactions
  • Problems with maternal hormones
  • Nerves, chemicals, and enzymes produced by the body that do not interact with the pylorus correctly (Nitric oxide, which is a chemical that helps to regulate the pyloric muscles, may play a role.)

Publication Review By: Stanley J. Swierzewski, III, M.D.

Published: 27 Aug 2008

Last Modified: 01 Oct 2015