Female to Male Changes

Females transitioning to males (FTM) may experience the following permanent effects of testosterone:

  • Atrophy of the uterus and ovaries, resulting in sterility
  • Baldness; hair loss, especially at temples and crown of head
  • Beard and mustache growth
  • Deepening of the voice
  • Enlargement of the clitoris
  • Increased growth of body hair
  • Sterility

Temporary changes, which are reversible after HT is stopped, include the following:

  • Behavioral developments associated with testosterone production during male puberty:
    • Aggression
    • Increased libido
  • Development of acne, similar to male puberty
  • Increased muscle mass and strength
  • Increase in number of red blood cells
  • Redistribution of fat from breasts, hips, and thighs to abdominal area

Increased risks associated with FTM testosterone therapy include the following:

  • Breast cancer
  • Cancer of endometrium
  • Diabetes
  • High cholesterol
  • Hypertension
  • Liver disease

Tobacco increases a person's risk for disease and complications. A general medical checkup is necessary before treatment, as well as a review of patient and family health history.

Publication Review By: Stanley J. Swierzewski, III, M.D.

Published: 31 Jul 2001

Last Modified: 08 Oct 2015